副詞 to begin with:

1. before now
   同義詞：in the first place, earlier, in the beginning, originally

1. Drinking make such fool of people, and people is such fool to begin with, that it's compound a felony.
   酗酒令人如此糊涂。而人本來就是糊涂，所以酗酒無非就等于是以罰款免人重罪罷了。
2. TO begin with, she is too young for that kind of job.
   首先，她做這種工作年紀還太輕。
3. I have several choices what to do. To begin with, I could do nothing!
   怎么干，我有好幾種選擇。首先，我什么也干不了！
4. I have to begin with an apology.
   我得首先表示歉意。